Endotoxin tolerance in monocytes can be mitigated by 2-interferon
نویسندگان
چکیده
منابع مشابه
Endotoxin tolerance in monocytes can be mitigated by α2-interferon.
Endotoxin tolerance is characterized by diminished expression of inflammatory cytokines after sequential exposure to Toll-like receptor stimuli. Many mechanisms contribute to tolerance; however, chromatin remodeling appears to be the most significant regulator. The type II interferon, IFN-γ, has been recognized as being able to reverse or abrogate the establishment of tolerance. Type I interfer...
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ژورنال
عنوان ژورنال: Journal of Leukocyte Biology
سال: 2015
ISSN: 0741-5400
DOI: 10.1189/jlb.4a0914-450rr